10 Ways Inflammation Impacts Your Health in 2025

Inflammation is a natural immune response to injury or infection, essential for healing in the short term. However, when inflammation becomes chronic, it can negatively impact various systems throughout the body, increasing the risk for numerous diseases and health conditions. Here’s a look at ten key stats revealing how inflammation intersects with health and wellness.


10 Short Stats To Hit The Point Home

  1. Higher Dementia Risk: Midlife inflammation raises dementia risk 2-3 times.

  2. Mental Health Connection: 30% of people with depression show higher inflammation levels.

  3. Sleep and Inflammation: Poor sleep increases inflammation by up to 60%.

  4. Exercise Benefit: Regular exercise can reduce inflammatory markers by 20%.

  5. Diet Impact: Processed foods increase inflammation, while Mediterranean diets decrease it by 25%.

  6. Asthma Trigger: Inflammation causes 80% of asthma cases.

  7. IBD Prevalence: Over 3 million U.S. adults suffer from inflammation-driven bowel diseases.

  8. Obesity Link: 40% of people with obesity have chronic low-grade inflammation.

  9. Cancer Risk: 20% of cancers are associated with chronic inflammatory conditions.

  10. Aging: Aging naturally raises inflammation, increasing disease risks.


1. Higher Dementia Risk with Chronic Inflammation

Dementia and Chronic Inflammation


Studies show that individuals with elevated inflammatory markers in midlife face a significantly increased risk of dementia later in life. Chronic inflammation can damage neurons and impair cognitive function over time, making conditions like Alzheimer’s and other types of dementia more likely. Since dementia affects memory, reasoning, and the ability to perform everyday tasks, addressing and managing inflammation early on could be key to preserving cognitive health as we age. By reducing long-term inflammation, individuals may protect their mental clarity and quality of life in their later years.

2. Mental Health Connection to Inflammation


In recent research, nearly 30% of people diagnosed with depression also had elevated levels of C-reactive protein (CRP), a primary marker for inflammation. This link between mental health and inflammation is sparking interest in inflammation-targeted treatments for mood disorders. Chronic inflammation can disrupt neurotransmitters like serotonin, contributing to persistent feelings of sadness, anxiety, and fatigue. For individuals struggling with depression, managing inflammation may offer new hope for improving mood and well-being while reducing the devastating impact depression can have on daily life.

3. Poor Sleep Raises Inflammation

Poor Sleep and inflammation


Poor-quality sleep or chronic sleep deprivation can significantly raise inflammatory cytokines by as much as 60%. Sleep is essential for the body’s repair processes, and lack of it triggers an inflammatory response that, over time, can lead to an increased risk of heart disease, diabetes, and even premature aging. By prioritizing restful sleep, individuals can support their body’s natural defenses, reducing inflammation and improving both physical and mental health outcomes. Addressing sleep quality is a vital, often overlooked strategy to combat inflammation and its harmful effects.

4. Exercise’s Role in Lowering Inflammatory Markers


Regular physical activity can lower CRP and other inflammatory markers by up to 20%, which is especially beneficial for people who are overweight or lead a sedentary lifestyle. Exercise activates anti-inflammatory pathways, reduces visceral fat, and supports overall immune function, making it a powerful tool for reducing inflammation. Even moderate exercise, such as walking or swimming, can improve circulation and boost health outcomes. Reducing inflammation through consistent movement not only lowers disease risk but also promotes longevity and enhanced quality of life.

5. Diet’s Effect on Inflammation

Bad Diet and Increased Inflammation


Diets high in refined sugars, trans fats, and processed foods can increase inflammation markers by as much as 30%, exacerbating the risk of chronic diseases. Conversely, anti-inflammatory diets like the Mediterranean diet—rich in omega-3s, fruits, vegetables, and whole grains—can decrease inflammation levels by around 25%. These dietary choices significantly impact overall health by promoting a balanced immune response. By reducing inflammatory foods and increasing anti-inflammatory choices, individuals may lower their risks for diseases like diabetes, arthritis, and cardiovascular issues.

6. Inflammation as a Major Asthma Trigger


Approximately 80% of asthma cases involve inflammation in the airways, often triggered by environmental factors like pollution, allergens, or respiratory infections. Chronic inflammation can restrict airflow, making it difficult for people with asthma to breathe and exacerbating symptoms. For the millions affected, managing airway inflammation is crucial in preventing asthma attacks and reducing dependency on medications. Reducing exposure to allergens and pollution, coupled with a focus on anti-inflammatory approaches, can empower people with asthma to breathe easier and lead more active lives.

7. Inflammatory Bowel Diseases Affect Millions

IBS and HBOT. How HBOT Helps lower inflammation


Inflammatory bowel diseases (IBD), like Crohn’s disease and ulcerative colitis, impact more than 3 million adults in the U.S. alone. These conditions, driven by chronic inflammation in the digestive tract, cause debilitating symptoms such as abdominal pain, diarrhea, and fatigue. The ongoing inflammation not only affects digestion but can also lead to severe complications like malnutrition and increased colon cancer risk. Managing inflammation is essential for symptom relief and preventing disease progression, making anti-inflammatory diets, stress management, and targeted therapies invaluable for IBD patients.

8. Obesity and Chronic Low-Grade Inflammation


About 40% of adults in the U.S. are considered obese, and this excess weight, especially around the abdomen, is linked to chronic low-grade inflammation. Fat cells produce pro-inflammatory chemicals that place additional strain on the immune system, increasing the risk for conditions like type 2 diabetes, liver disease, and heart disease. Addressing obesity through lifestyle changes can substantially reduce inflammation, improving both metabolic health and quality of life. By tackling this root cause, people may reduce their likelihood of developing further health complications associated with chronic inflammation.

9. Cancer Linked to Inflammatory Conditions

Cancer patient before HBOT


Chronic inflammation contributes to approximately 20% of cancers, particularly in the stomach, liver, and colon. Inflammatory processes can lead to cellular mutations and a microenvironment that fosters tumor growth. For individuals with persistent inflammatory conditions, the risk of cancer development underscores the need for inflammation management as a preventive measure. By addressing chronic inflammation through diet, lifestyle adjustments, and medical interventions, the potential for cancer development may be significantly reduced, offering an essential pathway to improved health outcomes.

10. “Inflammaging” and Age-Related Disease


As people age, chronic inflammation naturally increases in a process known as “inflammaging.” This low-grade, persistent inflammation is associated with higher risks for diseases like osteoporosis, cardiovascular issues, and Alzheimer’s. The effects of inflammaging extend beyond physical ailments, also impacting cognitive function and emotional well-being. Reducing inflammation through lifestyle choices like healthy eating, regular exercise, and stress management may help individuals age more healthfully, minimizing disease risks and preserving quality of life.


Can Hyperbaric Oxygen Help Decrease Chronic Inflammation?

HBOT Chamber For inflammation

Hyperbaric oxygen therapy (HBOT) has been shown to reduce inflammation at the cellular level by affecting the body’s genetic expression and modulating inflammatory responses.

During HBOT, increased oxygen levels can stimulate the activation of specific genes associated with tissue repair, cellular growth, and immune modulation. This process helps downregulate pro-inflammatory genes while promoting anti-inflammatory pathways. By influencing genetic expression, HBOT not only reduces chronic inflammation but also helps repair damaged tissues, improving overall immune function and recovery.

These genetic shifts support the body’s natural healing processes, making HBOT an appealing option for individuals with conditions where inflammation plays a key role, such as arthritis, autoimmune disorders, and sports injuries.

HBOT also decreases the production of inflammatory cytokines—proteins that can trigger and sustain inflammation within the body. By enhancing oxygen saturation, HBOT helps reduce the presence of pro-inflammatory cytokines like TNF-alpha, IL-1, and IL-6, which are often elevated in chronic inflammatory conditions.

Simultaneously, it increases anti-inflammatory cytokines that help restore immune balance and promote healing.

This cytokine regulation not only lessens pain and swelling associated with inflammation but also decreases the risk of chronic health complications linked to long-term inflammation, such as cardiovascular diseases, diabetes, and certain cancers.

What Does This Mean For You?

In summary, hyperbaric oxygen therapy (HBOT) emerges as a powerful tool in the fight against chronic inflammation. By leveraging the body’s genetic mechanisms and regulating cytokine production, HBOT offers a multifaceted approach to reducing inflammation and promoting healing. This innovative treatment not only addresses the symptoms of inflammatory conditions but also targets their underlying causes, fostering a healthier immune response.

As research continues to illuminate the benefits of HBOT, its potential applications in managing inflammation-related diseases become increasingly clear. By integrating HBOT into healthcare practices, patients can experience improved outcomes, enhanced quality of life, and a proactive path toward better health.

Embracing the science behind HBOT opens doors to new therapeutic possibilities and a brighter future for those affected by chronic inflammation.

Clarity Hyperbarics Des Moines Iowa
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Inflammaging: Effective Strategies to Combat Age-Related Inflammation